Toxicity of Ultrafine Nickel Particles in Lungs after Intratracheal Instillation
نویسندگان
چکیده
منابع مشابه
Comparative toxicity of standard nickel and ultrafine nickel in lung after intratracheal instillation.
A comparison was made of the bronchoalveolar lavage fluid (BALF) response to ultrafine nickel (Uf-Ni) and standard-sized nickel (Std-Ni). Rats were intratracheally instilled with 0, 0.1, 0.5, 1 and 5 mg Uf-Ni and Std-Ni, respectively. At 3 d after instillation, the body weight and wet lung weight were determined. At the same time, BALF was analyzed for lactate dehydrogenase (LDH), total protein...
متن کاملPulmonary toxicity following an intratracheal instillation of nickel oxide nanoparticle agglomerates.
OBJECTIVE We examined the pulmonary toxicity of nickel oxide nanoparticle agglomerates in the rat lung following an intratracheal instillation. METHODS The weighted average surface primary diameter of nickel oxide nanoparticles was 8.41 nm, and the count median diameter of nickel oxide nanoparticle agglomerates suspended in saline was 1.34 µm. Male Wistar rats were exposed to 1 mg (3.3 mg/kg)...
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OBJECTIVE Titanium dioxide nanoparticles are widely used as UV filters in cosmetics and as a photocatalyst. We evaluated pulmonary responses to different crystal forms of TiO2 nanoparticles. METHODS We used 4 different TiO2 samples with similar specific surface areas (anatase, rutile, amorphous, and P25). Each sample was suspended in distilled water and intratracheally instilled to male Wiste...
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متن کاملToxicity of Nicotine by Repeated Intratracheal Instillation to F344 Rats
In vivo, nicotine in cigarette smoke induces various effects not only on the respiratory system but also the central and peripheral nerve systems, circulatory organs and digestive organs, and there is a possibility of promotion of lung tumorigenesis. The present experiment was conducted to examine histopathological changes caused by nicotine in the lung with repeated intratracheal instillation ...
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ژورنال
عنوان ژورنال: Journal of Occupational Health
سال: 1998
ISSN: 1341-9145,1348-9585
DOI: 10.1539/joh.40.171